Microsatellites — Evolution and Applications
نویسندگان
چکیده
منابع مشابه
Evolution and Applications of Pine Microsatellites
The evolution of microsatellites was studied within and between the pine species. Sequences showed that microsatellites do not necessarily mutate in a stepwise fashion and that size homoplasy is common due to flanking sequence and repeat area changes within and between the species. Thus, some assumptions of statistical methods based on changes in repeat numbers may not hold. Sequences from cros...
متن کاملOrigin, evolution and genome distribution of microsatellites
Microsatellites, or simple sequence repeats (SSRs), have been the most widely applied class of molecular markers used in genetic studies, with applications in many fields of genetics including genetic conservation, population genetics, molecular breeding, and paternity testing. This range of applications is due to the fact that microsatellite markers are co-dominant and multi-allelic, are highl...
متن کاملMicrosatellites within genes: structure, function, and evolution.
Recently, increasingly more microsatellites, or simple sequence repeats (SSRs) have been found and characterized within protein-coding genes and their untranslated regions (UTRs). These data provide useful information to study possible SSR functions. Here, we review SSR distributions within expressed sequence tags (ESTs) and genes including protein-coding, 3'-UTRs and 5'-UTRs, and introns; and ...
متن کاملGenome evolution: Are microsatellites really simple sequences?
In 1989, the world started to look much brighter for genome mappers and behavioral ecologists: the polymerase chain reaction (PCR) and a type of sequence known as a microsatellite were brought together in the development of potentially powerful new methods for mapping genomes. Microsatellites seemed to have almost all the features required by those seeking a simple molecular way of tracking reg...
متن کاملEvolution of Coding Microsatellites in Primate Genomes
Microsatellites (SSRs) are highly susceptible to expansions and contractions. When located in a coding sequence, the insertion or the deletion of a single unit for a mono-, di-, tetra-, or penta(nucleotide)-SSR creates a frameshift. As a consequence, one would expect to find only very few of these SSRs in coding sequences because of their strong deleterious potential. Unexpectedly, genomes cont...
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ژورنال
عنوان ژورنال: Heredity
سال: 1999
ISSN: 0018-067X,1365-2540
DOI: 10.1038/sj.hdy.6886482